[EXECUTION VERSION Mindray Medical International Limited 4,000,000 American Depositary Shares (Par Value HK$0.001 Per Share) UNDERWRITING AGREEMENT March 3, 2010 JEFFERIES & COMPANY, INC. Ladies and Gentlemen: Introductory. Company Underwriter ADSs Ordinary Shares Firm ADSs Optional ADSs Offered ADSs Firm Shares Optional Shares Offered Shares Deposit Agreement Depositary ADRs Commission Base Prospectus Securities Act Exchange Act Registration Statement Preliminary Prospectus] [4 March 2010 th Mindray Medical International Limited DIRECT LINE: 852 2842 9500 Shenzhen 518057 Dear Sirs, Mindray Medical International Limited Company Registration Statement Securities Act Offering Shares ADSs We have acted as special Cayman legal counsel to Mindray Medical International Limited (the “ For the purposes of giving this opinion we have examined copies of the following documents: (i)] [[O’MELVENY & MYERS LLP LETTERHEAD] th Mindray Medical International Limited RE: 4,600,000 AMERICAN DEPOSITARY SHARES (THE “ADSS”), REPRESENTING 4,600,000 CLASS A ORDINARY SHARES OF MINDRAY MEDICAL INTERNATIONAL LIMITED (THE “COMPANY”) Ladies and Gentlemen: Respectfully submitted, EX-8.1 4 h04048exv8w1.htm EX-8.1] [Mindray Medical International Limited Announces Pricing of a Public Offering of American Depositary Shares SHENZHEN, China, March 4, 2010 — Mindray Medical International Limited (NYSE: MR) (“Mindray” or the “Company”), a leading developer, manufacturer and marketer of medical devices worldwide, today announced the pricing of a public offering of 4,000,000 American depositary shares (“ADSs”), representing 4,000,000 ordinary shares of the]

[• our goals and strategies; • our future business development, financial condition and results of operations, including our unaudited operating results for the year ended December 31, 2009; • the projected growth of the medical device industry in China and internationally; • the effects of the current global economic crisis and global macroeconomic conditions on our business; • the effects]

[EXECUTION VERSION Mindray Medical International Limited 4,000,000 American Depositary Shares (Par Value HK$0.001 Per Share) UNDERWRITINGREEMENT March3, 2010 JEFFERIES &MPANY, Ladies and Gentlemen: Introductory.mpany UnderwriterSs Ordinary Shares FirmSs OptionalSs OfferedSs Firm Shares Optional Shares Offered Shares Depositreement DepositaryRsmmission Base Prospectus] [4 March2010 th Mindray Medical International Limited DIRECT LINE: 852 2842 9500 Shenzhen 518057 Dear Sirs, Mindray Medical International Limitedmpany Registration Statement Securities Act Offering SharesSs We have actedecialyman legalunsel to Mindray Medical International Limited (the For the purposes of giving this opinion we have examinedpies of the following documents:] [[OMELVENY & MYERS LETTERHEAD] th Mindray Medical International Limited RE: 4,600,000 AMERICAN DEPOSITARY SHARES (THESS), REPRESENTING 4,600,000 CLASS A ORDINARY SHARES OF MINDRAY MEDICAL INTERNATIONAL LIMITED (THEMPANY) Ladies and Gentlemen: Respectfully submitted, EX-8.1 h04048exv8w1.htm 4 EX-8.1] [Mindray Medical International Limited Announces Pricing of a Public Offering of American Depositary Shares SHENZHEN, China, March4, 2010 Mindray Medical International Limited (NYSE: MR) (Mindray or thempany), a leading developer, manufacturer and marketer of medical devices worldwide, today announced the pricing of a public offering of 4,000,000 American depositary shares (ADSs), representing 4,000,000 ordinary shares]

[our goals and strategies; our future business development, financialndition and results of operations,luding our unaudited operating results for the year ended December31, 2009; the projected growth of the medical device industry in China and internationally; the effects of the current global economic crisis and global macroeconomicnditions on our business;]