MR [Mindray Medical International] 6-K: our goals and strategies; our future business development,

[our goals and strategies; our future business development, financialndition and results of operations,luding our unaudited operating results for the year ended December31, 2009; the projected growth of the medical device industry in China and internationally; the effects of the current global economic crisis and global macroeconomicnditions on our business;]

MR [Mindray Medical International] 424B5: (Original Filing)

[CALCULATION OF REGISTRATION FEE Proposed maximum Proposed maximum Title of each class of Amount to be offering price pergregate offering Amount of securities to be registered RegisteredS price registration fee(3) ClassA ordinary shares, par value HK$0.001 per share(1) 4,600,000 (2) $ 38.20 $ 175,720,000 $ 12,528.84 (1) American depositary shares, orSs, issuable upon deposit of]

MR [Mindray Medical International] 424B5: CALCULATION OF REGISTRATION FEE Proposed maximum Proposed maximum

[CALCULATION OF REGISTRATION FEE Proposed maximum Proposed maximum Title of each class of Amount to be offering price pergregate offering Amount of securities to be registered RegisteredS price registration fee(3) ClassA ordinary shares, par value HK$0.001 per share(1) 4,600,000 (2) $ 38.20 $ 175,720,000 $ 12,528.84 (1) American depositary shares, orSs, issuable upon deposit of]

MR [Mindray Medical International] 6-K: EXECUTION VERSION Mindray Medical International Limited 4,000,000 American

[EXECUTION VERSION Mindray Medical International Limited 4,000,000 American Depositary Shares (Par Value HK$0.001 Per Share) UNDERWRITINGREEMENT March3, 2010 JEFFERIES &MPANY, Ladies and Gentlemen: Introductory.mpany UnderwriterSs Ordinary Shares FirmSs OptionalSs OfferedSs Firm Shares Optional Shares Offered Shares Depositreement DepositaryRsmmission Base Prospectus] [4 March2010 th Mindray Medical International Limited DIRECT LINE: 852 2842 9500 Shenzhen 518057 Dear Sirs, Mindray Medical International Limitedmpany Registration Statement Securities Act Offering SharesSs We have actedecialyman legalunsel to Mindray Medical International Limited (the For the purposes of giving this opinion we have examinedpies of the following documents:] [[OMELVENY & MYERS LETTERHEAD] th Mindray Medical International Limited RE: 4,600,000 AMERICAN DEPOSITARY SHARES (THESS), REPRESENTING 4,600,000 CLASS A ORDINARY SHARES OF MINDRAY MEDICAL INTERNATIONAL LIMITED (THEMPANY) Ladies and Gentlemen: Respectfully submitted, EX-8.1 h04048exv8w1.htm 4 EX-8.1] [Mindray Medical International Limited Announces Pricing of a Public Offering of American Depositary Shares SHENZHEN, China, March4, 2010 Mindray Medical International Limited (NYSE: MR) (Mindray or thempany), a leading developer, manufacturer and marketer of medical devices worldwide, today announced the pricing of a public offering of 4,000,000 American depositary shares (ADSs), representing 4,000,000 ordinary shares]

MR [Mindray Medical International] 424B5: CALCULATION OF REGISTRATION FEE Proposed maximum Proposed maximum

[CALCULATION OF REGISTRATION FEE Proposed maximum Proposed maximum Title of each class of Amount to be offering price pergregate offering Amount of securities to be registered RegisteredS price registration fee(3) ClassA ordinary shares, par value HK$0.001 per share(1) 4,600,000 (2) $ 38.20 $ 175,720,000 $ 12,528.84 (1) American depositary shares, orSs, issuable upon deposit of]

MR [Mindray Medical International] 6-K: our goals and strategies; our future business development,

[our goals and strategies; our future business development, financialndition and results of operations,luding our unaudited operating results for the year ended December31, 2009; the projected growth of the medical device industry in China and internationally; the effects of the current global economic crisis and global macroeconomicnditions on our business;]

MR [Mindray Medical International] 424B5: The information in this prospectus supplement is notmplete

[The information in this prospectus supplement is notmplete and may be changed. This prospectus supplement is not an offer to sell these securities and is not an offer to buy these securities in any jurisdiction where such offer orle is not permitted. SUBJECT TOMPLETION,TED MARCH3, 2010 Preliminary Prospectus Supplement]

MR [Mindray Medical International] 424B5: The information in this prospectus supplement is notmplete

[The information in this prospectus supplement is notmplete and may be changed. This prospectus supplement is not an offer to sell these securities and is not an offer to buy these securities in any jurisdiction where such offer orle is not permitted. SUBJECT TOMPLETION,TED MARCH3, 2010 Preliminary Prospectus Supplement]

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